Category for medical terms

What is a monoclonal antibody?

A monoclonal antibody or mAb is an antibody produced in the laboratory from a single ancestral plasma cell

What Is Non-Hodgkin Lymphoma?

Non-Hodgkin lymphoma (also known as non-Hodgkin’s lymphoma or NHL) is a cancer of the lymphocytes, a type of white blood cells and an important part of the immune system.

What is INI1 and SMARCA4?

INI1 and SMARCA4 are subunits of SWI/SNF, a chromatin modifying protein complex, which opposes the activity of PRC2, the complex within which EZH2 resides.

What is Chromatin Remodelling?

Chromatin remodeling is a change in this gene-specific chromatin structure that can change which genes are expressed and which are silenced.

What is an SPA or Special Protocol Assessment?

SPA or Special Protocol Assessment is an agreement arrived at between the FDA and a drug sponsor planning a pivotal trial.

What is Intent-to-treat population or ITT?

Intent-to treat population is the total number of patients randomized at the beginning of a trial.

What is NME/NCE?

A New Molecular Entity or NME and a new chemical entity or NCE.

What is MDS – Myelodysplastic syndrome?

What is MDS - Myelodysplastic syndrome?

What is Statistical significance and p-value ?

Statistical significance and p-value are key statistical measures used in clinical trials.

What is a Hypomethylating agent or HMA?

Hypomethylating agent - or HMA, are hypomethylating or demethylating agents.