What are Small Molecule drugs?

What are Small Molecule drugs?

As opposed to a biologic like a monoclonal antibody, a small molecule drug is an organic non-biologic drug with low molecular weight in the range of a few hundred daltons. It is relatively easier to develop and manufacture, but also equally easy to copy as a generic. Small molecule drugs penetrate cell membrane easily, have generally lower side effects due to their lower immunogenicity, and generally cost a fraction of biologics. Broadly, a small molecule’s non-branded copy is called a generic, while a biologic’s non-branded copy is called a biosimilar or biosim.

What is a monoclonal antibody?

A monoclonal antibody or mAb is an antibody produced in the laboratory from a single ancestral plasma cell

What Is Non-Hodgkin Lymphoma?

Non-Hodgkin lymphoma (also known as non-Hodgkin’s lymphoma or NHL) is a cancer of the lymphocytes, a type of white blood cells and an important part of the immune system.

What is INI1 and SMARCA4?

INI1 and SMARCA4 are subunits of SWI/SNF, a chromatin modifying protein complex, which opposes the activity of PRC2, the complex within which EZH2 resides.