INI1 and SMARCA4 are subunits of SWI/SNF, a chromatin modifying protein complex, which opposes the activity of PRC2, the complex within which EZH2 resides.
This author has yet to write their bio.Meanwhile lets just say that we are proud DrUKM contributed a whooping 49 entries.
Entries by DrUKM
Chromatin remodeling is a change in this gene-specific chromatin structure that can change which genes are expressed and which are silenced.
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SPA or Special Protocol Assessment is an agreement arrived at between the FDA and a drug sponsor planning a pivotal trial.
Intent-to treat population is the total number of patients randomized at the beginning of a trial.
A New Molecular Entity or NME and a new chemical entity or NCE.
What is MDS - Myelodysplastic syndrome?
Statistical significance and p-value are key statistical measures used in clinical trials.
Hypomethylating agent - or HMA, are hypomethylating or demethylating agents.